No grounds for abandoning sedation

Anxiety in Children Undergoing VCUG: Sedation or No Sedation?

BACKGROUND Voiding cystourethrograms are distressing for children and parents. Nonpharmacological methods reduce distress. Pharmacological interventions for VCUG focus on sedation as well as analgesia, anxiolysis, and amnesia. Sedation has cost, time, and safety issues. Which agents and route should we use? Are we sure that sedation does not influence the ability to diagnose vesicoureteric refl...

Coffee: grounds for concern?

C aff eine is the most widely ingested nonregulated substance on earth. A major portion of this drug is consumed as coff ee, with an annual production of over 7.8 million metric tons. Over 2.5 billion cups of coff ee are consumed worldwide each day. Given its popularity, it is hard to conceive of how Western civilization might begin each workday without this critical liquid allotment. Despite t...

New Grounds for Drinking Coffee

Follicular lymphoma: grounds for optimism.

The fact that follicular lymphoma is characterized by a specific immune phenotype and a nonrandom chromosomal translocation which may be detected at the molecular level makes it possible to design novel therapeutic strategies for curative therapy. Molecular markers may be used to test hypotheses. Some current causes for optimism are reviewed.

No further research needed: abandoning the Hospital and Anxiety Depression Scale (HADS).

Cosco and colleagues [this issue] provide a well done and transparently reported systematic review of the Hospital and Anxiety Depression Scale (HADS) literature of the past decade. They conclude that the underlying structure of the HADS is inconsistent across samples and highly dependent on the statistical methods used to establish that structure. The implication is that the HADS is not a depe...